5/10/25 individually packed test cassettes for detection of D-Dimer in human whole blood and plasma
Package contents:
5/10/25 test cassettes
5/10/25 disposable pipettes
1/2/5 buffer bottle(s)
1 package insert
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The NADAL® D-Dimer Test is used for the qualitative detection of D-Dimer in human whole blood and plasma. The test is used as an aid in the assessment and evaluation of patients with suspected disseminated intravascular coagulation (DIC), deep vein thrombosis (DVT) and pulmonary embolism (PE).
During blood coagulation process, fibrinogen is converted to fibrin by the activation of thrombin. The resulting fibrin monomers polymerise to form a soluble gel of non-crosslinked fibrin. This fibrin gel is then converted to cross-linked fibrin by thrombin activated factor XIII to form an insoluble fibrin clot. Production of plasmin, the major clot-lysing enzyme, is triggered when a fibrin clot is formed. Although fibrinogen and fibrin are both cleaved by the fibrinolytic enzyme plasmin to yield degradation products, only degradation products from cross-linked fibrin contain D-Dimer and are called cross-linked fibrin degradation products. Therefore, fibrin derivatives in human blood or plasma containing D-Dimer are a specific marker of fibrinolysis. The detection limit of the NADAL® D-Dimer Test is 500 ng/mL D-Dimer.
