10 individually packed test cassettes for detection of rotavirus in human fecal specimens to aid in the diagnosis of rotavirus infection
Package contents:
10 Test cassettes
10 disposable pipettes
10 specimen collection tubes with buffer
1 package insert
Exclusively for professional users
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The NADAL® Rotavirus Test by nal von minden is a rapid chromatographic immunoassay for the qualitative detection of rotavirus in human fecal specimens to aid in the diagnosis of rotavirus infection (rapid test). The test is designed for professional in-vitro diagnostic use only.
Rotavirus is the most common agent responsible for acute gastroenteritis, mainly in young children. Its discovery in 1973 and its association with infantile gastroenteritis represented a very important advancement in the study of gastroenteritis and the finding that it was not caused by an acute bacterial infection. Rotavirus is transmitted by an oral-faecal route with an incubation period of 1-3 days. Although specimen collections taken within the second and fifth day of the illness are ideal for antigen detection, the rotavirus may still be found while diarrhea continues. Rotaviral gastroenteritis may result in mortality for demographics at risk such as infants, the elderly, and immunocompromised patients. In temperate climates, rotavirus infections occur mainly in the winter months. Endemics, as well as epidemics, affecting some thousand people have been reported. With hospitalised children suffering from acute entric disease up to 50% of the analysed specimen were positive for rotavirus. The viruses replicate in the cell nucleus and tend to be host species specifically producing a characteristic cytopathic effect (CPE). Because rotavirus is extremely difficult to culture, it is unusual to use virus isolation in diagnosing an infection. Instead, a variety of techniques have been developed to detect rotavirus in feces. The NADAL® Rotavirus Test is a rapid chromatographic immunoassay for the qualitative detection of rotavirus in human feces specimen, providing results in 10 minutes. The test utilises antibodies specific for rotavirus to selectively detect rotavirus from human feces specimens.