10 individually packed test cassettes for detection of and differentiation of norovirus antigens of genogroups I and II (GI and GII), as well as rotaviruses and adenoviruses in human faecal specimens
Package contents:
10 test cassettes
10 disposable pipettes
10 specimen collection tubes with buffer
1 package insert
Exclusively for professional users
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The NADAL® Norovirus GI/GII+Rota-Adenovirus Test is a rapid chromatographic immunoassay for the qualitative detection and differentiation of norovirus antigens of genogroups I and II (GI and GII), as well as rotaviruses and adenoviruses in human faecal specimens. The test is intended for use as an aid in the diagnosis of norovirus, rotavirus and adenovirus infections and is designed for professional use only.
Acute gastroenteritis is a common disorder in young children, and the associated dehydration is both a leading cause of admission to hospital in industrialised countries and a major cause of mortality in developing countries. Symptoms may include diarrhoea, vomiting and abdominal pain. Fever, a lack of energy and dehydration may also occur. This typically lasts less than two weeks. Enteric viruses have been recognised as the most significant etiological agents of the disease, with rotavirus, adenovirus 40/41, norovirus and astrovirus currently being recognised as the most significant pathogens of childhood viral gastroenteritis. Rotavirus is the most common cause of gastroenteritis in children. Viruses cause approximately 70% of episodes of infectious diarrhoea in the paediatric age group. Adenoviruses, primarily Ad40 and Ad41, are a leading cause of diarrhoea in children, second only to rotaviruses. Infections are most frequently observed in children under two years old, but have been found in patients of all ages. Further studies indicate that adenoviruses are associated with 4-15% of all hospitalised cases of viral gastroenteritis. Norovirus is a leading cause of gastroenteritis among adults in United States of America, causing more than 90% of outbreaks. These localised epidemics typically occur when groups of people spend time in close physical proximity to each other, such as on cruise ships, in hospitals or in restaurants. Noroviruses commonly isolated in cases of acute gastroenteritis belong to two genogroups: GI and GII. Patients may remain infectious even after their diarrhoea has cleared up. Gastroenteritis is typically diagnosed clinically, based on a person's signs and symptoms. However, stool cultures should be performed in those with blood in their stool, those who may have been exposed to food poisoning and in those who have recently traveled to developing countries. They may also be appropriate for children under 5 years old, elderly people, and those with poor immune function. Diagnostic testing may also be carried out for monitoring.
