NADAL® Legionella/S. pneumoniae test cassette


10 individually packed test cassettes for detection of Legionella pneumophila and Streptococcus pneumoniae antigens in human urine.


Package contents:

10 Test cassettes

10 disposable pipettes

1 package insert


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Product description

The NADAL® Legionella/S. pneumoniae Test is a lateral flow, rapid immunochromatographic test for the qualitative detection of Legionella pneumophila and Streptococcus
pneumoniae antigens in human urine. The test is intended to be used as an aid in the diagnosis of Legionella infection (Legionnaires’ disease), pneumonia, meningitis and otitis.

Legionella are gram-negative bacteria associated with Pontiac fever and Legionnaires’ disease, leading to the infection of the upper respiratory tract and causing pneumonia, a pulmonary
disease. High fevers have been reported in many cases. An estimated 10,000 to 25,000 cases involving Legionella pneumophila infections occur in the USA annually. Approximately 5% to 30% of people with Legionnaires’ disease die as a result of infection. Extrapulmonary infections may be spread through the bloodstream or the lymph system, infecting the heart, brain, kidney, liver and/or spleen. Common methods for the detection of Legionella pneumophila include culture, direct fluorescent antibody testing, indirect fluorescent antibody, enzyme immunoassays and polymerase chain reaction. Streptococcus pneumoniae is a gram-positive bacterium, which was first isolated by Pasteur in 1881 from the saliva of a patient with
rabies. The chemical structure and antigenicity of the pneumococcal capsular polysaccharide, its association with virulence and role in human disease were explained over the
period from 1915 to 1945. Bacteria are lancet-shaped anaerobic organisms which are spread via respiratory droplets during close person-to-person contact, and which cause
serious diseases in humans: The 10 most common serotypes are estimated to account for about 62% of invasive disease worldwide. Streptococcus pneumoniae colonises upper
respiratory tract tissues, causing severe pneumonia and mild/acute earache/otitis. Pneumococci cause 13% to 19% of all cases of bacterial meningitis in the United States. One-quarter of patients with pneumococcal meningitis also have pneumonia. The clinical symptoms are generally similar to other forms of purulent bacterial meningitis and include
headaches, lethargy, vomiting, irritability, fever, nuchal rigidity, cranial signs, seizures and coma. The case-fatality of pneumococcal meningitis is roughly 30% but can be as high as
80% amongst the elderly. Bacterial pneumonia accounts for 12-16% of invasive pneumococcal disease in children aged 2 years and under, and S. pneumoniae has become the leading cause of bacterial meningitis in children under 5 years old in the United States. Antibiotic treatment is efficient even if more penicillin-resistant strains have been identified. Several vaccines are available, with varying efficiency, depending on patient factors such as age, chronic illnesses or immunodeficiency. Nevertheless, it has been demonstrated that vaccines provide protection against pneumococcal pneumonia.

More Information

More Information
SKU 572005
Testformat test cassette
Test evaluation Provides a qualitative test result
Sample type Urine
Detected parameter Legionella/S. pneumoniae
Package size 10 individually packed test cassettes
Detection time Test result after 10 minutes
Storage temperature The test should be stored at 4 - 30 °C
CE-Label Yes
Pathogentype Bacterial infection

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