10 individually packed test cassettes for detection of Entamoeba spp. antigens in human faecal specimens to aid in the diagnosis of amoebiasis
Package contents:
10 test cassettes
10 specimen collection tubes containing buffer
1 package insert
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The NADAL® Entamoeba Test is a rapid chromatographic immunoassay for the qualitative detection of Entamoeba spp. antigens in human faecal specimens to aid in the diagnosis of amoebiasis.
Amoebiasis is the infection of human gastrointestinal tract by Entamoeba histolytica, a protozoan parasite which is capable of invading intestinal mucosa and may spread to other organs, mainly to liver. Entamoeba dispar, an amoeba morphologically similar to E. histolytica that also colonises in human gut, has been recently recognised as a separate species with no invasive potential. The acceptance of E. dispar as a distinct but closely related protozoan species has had profound implications for epidemiology of amoebiasis, since most asymptomatic infections found worldwide are now attributed to this non-invasive amoeba. Invasive amoebiasis due to E. histolytica is more common in developing countries. In areas of endemic infection, a variety of conditions including ignorance, poverty, overcrowding, inadequate and contaminated water supplies and poor sanitation favour direct faecal-oral transmission of amoebas from one person to another. Being responsible for approximately 70 thousand deaths annually, amoebiasis is the fourth leading cause of death due to a protozoan infection after malaria, Chagas disease and leishmaniasis, and the third cause of morbidity in this organism group after malaria and trichomoniasis, according to the recent World Health Organisation estimate. Patients with dysentery have an average of three to five mucosanguineous evacuations per day, with moderate colic pain preceding discharge, and rectal tenesmus. In patients with bloody diarrhoea evacuations are also few but stools are composed of liquid faecal material stained with blood. While there is moderate colic pain, there is no rectal tenesmus. Fever and systemic manifestations are generally absent.
