5/40 individually packed test cassettes for detection of antibodies against Hepatitis C Virus (HCV) antigens in human whole blood, serum, plasma
Package contents:
5/40 test cassettes
5/40 disposable pipettes
1 buffer
1 package insert
Exclusively for professional users
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The Anti-HCV Test is a rapid chromatographic immunoassay for the qualitative detection of antibodies generated against proteins that are encoded by conserved sequences of CORE, NS3, NS4, NS5 parts of Hepatitis C virus (HCV) genome in human whole blood, serum and plasma.
Hepatitis C virus (HCV) is a major cause of chronic liver disease, frequently progressing to cirrhosis and increased risk of hepatocellular carcinoma. HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10.000 nucleotides and encodes a single polyprotein of about 3.000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with di_erences in response to treatment with interferon alpha. HCV can be classified into six genetically distinct genotypes and further subdivided into at least 70 subtypes, which dffer by approximately 30% and 15% at the nucleotide level, respectively. The dfferent genotypes may exhibit differing phenotypic properties. Immunochromatographic membrane tests can be performed in a few minutes and the results are read visually and could be suitable for use in laboratories that have limited facilities. In addition, even if there is no prophylactic HCV treatment after a needle-stick injury, it can be important to know rapidly the HCV status of a source patient.
