24 AFIAS test cassettes for the quantitative determination of follicle stimulating hormone (FSH) in human whole blood, serum or plasma.
Package contents:
24 AFIAS test cassettes
24 pipette tips
1 ID chip
1 package insert
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The AFIAS FSH Test a fluorescence immunoassay (FIA) for the quantitative determination of follicle stimulating hormone (FSH) in human whole blood, serum or plasma. It is used as an aid in the treatment and monitoring of FSH. For in vitro diagnostic use only.
Follicle stimulating hormone (FSH) is produced and released in the gonadotropic cells of the anterior pituitary. The α-subunits of LH, FSH, TSH and hCG are identical and consist of 92 amino acids. FSH has a β-subunit with 118 amino acids (FSHβ), which gives FSH its specific biological effect and interacts with the FSH receptor. FSH regulates development, growth, pubertal maturation and reproductive processes of the body. FSH and luteinising hormone (LH) act synergistically in reproduction. High serum FSH levels are most common in women who are going through menopause or have recently gone through menopause. High FSH levels indicate the absence of the normal limiting feedback mechanism, resulting in unrestrained pituitary FSH production. If high FSH levels occur during the reproductive years, it is pathological. Complaints with high FSH levels include: premature menopause (premature ovarian failure), poor ovarian reserve (premature ovarian ageing), gonadal dysgenesis, Turner syndrome, castration, Swyer syndrome, certain forms of adrenogenital syndrome (AGS), hypogonadism. Most of these conditions are associated with reduced fertility and/or infertility. Therefore, high FSH levels are a sign of fertility disorders.
